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High-potency topical steroids, often used as first-line therapy In the past, people with kidney transplants usually have taken steroids (such as prednisone) as one of their immunosuppressive medications to prevent. In severe or steroid-resistant rejection, use. 8%) with concomitant use of high corticosteroid doses. Majority of transplant centers continue to use corticosteroids despite the. A kidney transplant operation is when a healthy kidney from one person is placed in the body of another person with kidney disease. Mansoura: costbenefit of steroid avoidance in renal transplant patients: a. [4] steroid use after kidney transplantation is a classic example of a trade‐off between benefits and harms. Reducing the risk of rejection. (&lt;18years) undergoing renal transplantation. Depleting t-cell antibodies are used for treatment of steroid-resistant acute rejection and as induction therapy to reduce the intensity of. 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